Co-starred with Ed Harris and Julia Roberts in the comedy-drama "Stepmom"; also served as executive producer
Played small role in Robbins' feature directing debut "Bob Roberts"
Played the fictionalized heroine in the TV dramatization "F. Scott Fitzgerald and the Last of the Belles" (ABC)
Starred as a housewife investigating a murder in the comedy-drama "Compromising Positions"; was pregnant with first child during filming which was noticably visible in some scenes
Starred opposite Jude Law in "Alfie," a remake of the 1966 film starring Michael Caine
Was leading lady to Robert Redford in "The Great Waldo Pepper"
Acted with John Cassavetes and wife Gena Rowlands in Paul Mazursky's "Tempest," loosely based on Shakespeare's play
Co-starred as James Gandolfini's wife in "Romance & Cigarettes," directed by John Turturro
Co-starred opposite Dustin Hoffman in "Moonlight Mile"
Co-starred opposite Tommy Lee Jones in Paul Haggis' "In the Valley of Elah"
Made cameo appearance in Robbins' feature "The Cradle Will Rock"
Played the mother of twin sons (Edward Norton) in Tim Blake Nelson's "Leaves of Grass"
Portrayed older waitress who becomes involved with younger yuppie James Spader in "White Palace"
Voiced the dog Ivy in the feature "Cats & Dogs"
Cast as a movie star married to Gene Hackman who calls upon old friend detective Paul Newman for assistance in Robert Benton's "Twilight"
Cast as Richard Gere's wife in "Shall We Dance?" a remake of the 1996 Japanese film
Co-starred as Edda Ciano, the dictator's daughter in the HBO miniseries "Mussolini: The Decline and Fall of Il Duce"
First film with director Louis Malle, "Pretty Baby" playing Brooke Shields' prostitute mother
Guest starred on several episodes of Denis Leary's FX drama "Rescue Me"
Off-Broadway debut in "A Coupla White Chicks Sitting Around Talking"
Provided the voice for Coco La Bouche in the animated film "Rugrats in Paris - The Movie"
Reteamed with Malle for "Atlantic City"; earned first Best Actress Oscar nomination playing a young casino employee who falls for older Burt Lancaster
Returned to Broadway after more than 30 years as the elder ex-wife of a dying monarch, portrayed by Aussie actor Geoffrey Rush, in Eugene Ionesco's drama "Exit The King"
Starred as a single mother of a teenager in Wayne Wang's "Anywhere But Here"
Starred opposite Christopher Walken in the acclaimed PBS drama "Who Am I This Time?"
Acted on the daytime soap "Search for Tomorrow" (CBS, NBC)
Co-starred as Hemlock Society activist Janet Good in the Barry Levinson directed HBO film "You Don't Know Jack," about Dr. Jack Kevorkian, played by Al Pacino; earned an Emmy nomination for Outstanding Supporting Actress in a Miniseries or Movie
Co-starred with Goldie Hawn in "The Banger Sisters"
Had cameo role as painter Alice Neel in "Joe Gould's Secret," directed by Stanley Tucci
Love scene with Catherine Deneuve in Tony Scott's "The Hunger" created a minor furor
Made cameo appearance as herself in Robert Altman's "The Player," starring Robbins
Portrayed tobacco millionairess Doris Duke in the HBO film "Bernard and Doris"; earned Emmy, Golden Globe and SAG nominations for Best Actress in a TV-movie
Provided the voice of the Spider for "James and the Giant Peach"
Received a star on the Hollywood Walk of Fame
Co-starred in "Jeff, Who Lives at Home" opposite Jason Segel and Ed Helms
Re-teamed with Richard Gere as husband and wife in financial thriller "Arbitrage"
Played multiple roles in "Cloud Atlas," based on David Mitchell's 2004 novel; film co-directed by Andy Wachowski, Lana Wachowski, and Tom Tykwer
Co-starred with director Robert Redford in thriller "The Company You Keep"
Began voicing aunt Agatha in Ezra Koenig's anime series "Neo Yokio"
Joined the cast of "Ray Donovan"
Appeared in the drama "The Death and Life of John F. Donovan"
Had first regular TV role, appearing on the ABC daytime soap "A World Apart"
Made guest appearance on an episode of "Friends" (NBC) playing a soap opera actress; received Emmy nomination
Met companion Tim Robbins while co-starring in hit comedy "Bull Durham"
Played Mom Racer in the Wachowski brothers' live action film adaptation of the 1960s Japanese series "Speed Racer"
Played Orlando Bloom's mother in Cameron Crowe's drama "Elizabethtown"
Portrayed the matriarch of the March family in Gillian Armstrong's "Little Women"
Reteamed with Miller for "Lorenzo's Oil," earning her third Best Actress Academy Award nomination
Made screen debut in "Joe"; had accompanied then-husband Chris Sarandon to his audition for the film but she was hired instead
Co-starred as newlywed Janet in cult hit "The Rocky Horror Picture Show"
Co-starred with Geena Davis in the female buddy film "Thelma & Louise," directed by Ridley Scott; earned second Best Actress Oscar nomination
Made first film with director George Miller, "The Witches of Eastwick"
Picked up a fourth Best Actress Oscar nomination for her turn as a no-nonense Southern attorney in "The Client"
Played the title character's mother in "Igby Goes Down"; received a Golden Globe nomination for Best Supporting Actress
Made Broadway debut as Tricia Nixon in Gore Vidal's "An Evening With Richard Nixon and . . ."
Played the evil queen in Disney's modern-day animation and live-action fairy tale "Enchanted"
Played the grandmother of a young girl who is murdered in the film adaptation of Alice Sebold's bestseller "The Lovely Bones"
Starred in Robbins' "Dead Man Walking" opposite Sean Penn; finally won Oscar as Best Actress; Robbins' nomination as Best Director made them the first couple since Cassavetes and Rowlands to be jointly nominated for their work together
Appeared in Oliver Stone directed sequel "Wall Street: Money Never Sleeps"
Cast opposite Dwayne Johnson in action drama "Snitch"
Cast as Pearl in Melissa McCarthy vehicle "Tammy"
Appeared as the grandmother in transgender drama "3 Generations"
Played Bette Davis in biopic series "Feud"