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According to Hollywood Reporter pre-release news items, this film went into production as Manhattan Madness with Richard Boleslawski directing. After two days of shooting, Boleslawski reportedly left the picture to direct O'Shaughnessy's Boy. Following this, two other directors were assigned to the picture before George B. Seitz took over as the fourth and final director. This turmoil apparently caused many delays and interruptions in the shooting schedule. Boleslawski was later replaced by Harry Beaumont, who soon walked off the picture announcing that he was dissatisfied with the script. In late May, J. Walter Ruben was assigned to direct the picture, but he was sidetracked to direct Riff Raff.
Hollywood Reporter pre-production news items also noted that both Franchot Tone and Wallace Beery were considered for the male lead before Joel McCrea was assigned the part. According to Daily Variety, Tone did not take the part because M-G-M assigned him to replace Robert Montgomery in Mutiny on the Bounty. A Hollywood Reporter pre-release news item indicates that George Hanneman was assigned to retouch the script after Beaumont's departure. Early Hollywood Reporter production charts list actors Claude Gillingwater, Henry Bradley, Tom McGuire, Bill Dooley, Eddie Hart, Michael Marc, Tyler Brooke and Charles Lane in the cast, but their appearance in the released film has not been confirmed. Also, an early Hollywood Reporter production chart lists Ted Healy in the cast, but he did not appear in the released film. Modern sources list actor Dave O'Brien (Tap dancer) in the cast. Following the release of Woman Wanted, a Hollywood Reporter news item noted that, due to a studio error, too many names appeared in the writers credit in the preview credits. Only Fields, Silverstein and Collison were intended to receive writing credits.