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The working titles of this picture were Family Reunion, Family Affair, American Family and Sister Act. This picture was a sequel to Warner Bros. 1938 film Four Daughters. Production charts in Hollywood Reporter note that Fay Bainter was to cast in the picture, but her participation in the project is unconfirmed. The composition Symphonie Moderne, which Max Steiner wrote for this film, was later expanded and published. In 1941, William Keighley directed the Lane sisters in Four Mothers, which was also based on the Fannie Hurst story.