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The working title of this film was Sherlock Holmes Fights Back. The Sir Arthur Conan Doyle short story from which this film is based was first published in the United States in Collier's (5 December 1903) and is included in the collection The Return of Sherlock Holmes (London, 1905). This was the second film in the Universal "Sherlock Holmes" series, and the first to be directed by Roy William Neill, who went on to direct all subsequent Sherlock Holmes films at Universal. Dennis Hoey made his first appearance as "Inspector Lestrade," who became a recurring character in the Universal Holmes series. Later in 1943, character actor Robert O. Davis changed his stage name to Rudolph Anders, a variation on his character's name in this film.
Modern sources include Michael Mark (George) and Philip Van Zandt in the cast. Some modern sources also claim that noted character actor Henry Daniell played a bit part in the film, but he was not seen in the viewed print and it is doubtful that he actually appeared. For additional information on the series and other films featuring the Arthur Conan Doyle characters, consult the Series Index and see the entry below for Sherlock Holmes and the Voice of Terror, and the entries for Sherlock Holmes and The Hounds of the Baskervilles in the AFI Catalog of Feature Films, 1931-40; F3.4020 and F3.2009.