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The title card reads: "Edgar Rice Burroughs' Tarzan's Greatest Adventure." A statement in the opening credits reads: "Made with the cooperation of East African Films Services." Although several contemporary sources refer to the film as "A Sy Weintraub-Harvey Hayutin production," Hayutin is not listed in the onscreen credits and the only production company listed is Paramount.
Tarzan's Greatest Adventure was the first of the "Tarzan" films to be shot in Africa; the Los Angeles Examiner review specifies the location as Nairobi. According to the studio's official website, interiors were shot at Shepperton Studios in London. Italian actress Scilla Gabel made her American feature debut in Tarzan's Greatest Adventure.
Contemporary sources noted the fact that the character of "Jane" was not included in this film, and Cheetah appears only in the first few scenes. Many of the reviews and modern sources refer to Tarzan's Greatest Adventure as the best feature in the series. For more information about the series, see the entries for Tarzan, the Ape Man in AFI Catalog of Feature Films, 1931-40 and Tarzan Triumphs in AFI Catalog of Feature Films, 1941-50, and consult the Series Index.